Scientists Study How Keto Differs From Low-Fat Diets
The Journal of the American Medical Association recently published an in-depth article1 on ketosis, highlighting its place as a mainstay in the American nutritional world. The article previewed a study that consists of two phases: an in-home preparation phase, where participants eat a calorie-restricted diet of home-delivered meals. Those who lose at least 15 percent of their body weight will move on to the next phase: a three-month stay at a wooded lakefront in Ashland, Massachusetts.
This second phase of the study consists of 25 adults who will be randomly assigned one of three diets which consist of equal calories, but are made up of drastically different ingredients:
- A low-fat, high carbohydrate diet that’s high in added sugars
- A low-fat, high carbohydrate diet that’s low in added sugars
- A high-fat ketogenic diet
This trial will be the first of five that will take place over the next three years. The study will take a group of subjects who have already demonstrated an ability to lose weight based on diet and measure their changes in body fat mass and energy output. The goal is to determine if any of the diets have a unique effect on metabolism, given equal calorie intake, among the study participants.
The Keto Diet Takes Weight Off… And Keeps It Off
The motivation for this study was provided by a meta-analysis2 of 13 randomized control trials. The results of this meta-analysis indicated that people on keto diets tend to lose weight more consistently and keep it off for longer than people who try low-fat diets.
One of the study’s co-principal investigators is David S. Ludwig, MD, Ph.D., a professor of pediatrics and nutrition at Harvard Medical School and Harvard T.H. Chan School of Public Health. He states: “The quality of calories consumed may affect the number of calories burned. If this apparent metabolic benefit persists, it could play an important role in improving the success of long-term weight-loss maintenance.”
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